According to the research of breast cancer detected in women taking , usually more differentiated than it do not take women.
Masteron propionate increases mammographic breast density, which in some cases may adversely affect the radiological detection of breast cancer.
- Swelling of the liver
Against the background of the use of sex steroids, which include means , in rare cases benign, and even more rarely – malignant tumors of the liver. In some cases, these tumors have led to life-threatening intra-abdominal haemorrhage. When the pain in the upper abdomen, enlarged liver or signs of intra-abdominal bleeding in the differential diagnosis should take into account the probability of having liver cancer.
It is known that estrogens increase the lithogenic bile. Some women are predisposed to the development of gallstone disease during treatment with estrogens.
- other conditions
It should immediately discontinue treatment, the appearance of the first migraine or frequent and unusually severe headaches, as well as the appearance of other symptoms – possible precursors of thrombotic stroke brain.
The relationship between and the development of clinically significant hypertension has not been established. In women taking masteron propionate, described a slight increase in blood pressure, a clinically significant increase is rare. However, in some cases, in the development against the backdrop reception clinically significant hypertension can be considered the abolition masteron propionate.
In non-severe hepatic dysfunction, including various forms of hyperbilirubinemia, such as Dubin-Johnson syndrome or Rotor syndrome, need medical supervision and periodic liver function tests. If deterioration in liver function should be abolished.
When relapse cholestatic jaundice or cholestatic pruritus, observed for the first time during pregnancy or previous treatment sex steroid hormones, hormone replacement therapy should be discontinued immediately.
The need for special monitoring of women with moderately elevated levels of triglycerides. In such cases, the use of HRT may cause a further increase in the level of triglycerides in the blood, which increases the risk of acute pancreatitis.
Although HRT may influence the peripheral insulin resistance and glucose tolerance, need to change the treatment regimen of patients with diabetes during HRT, usually does not arise. However, women suffering from diabetes, during HRT should be monitored.
Some patients under the influence may develop undesirable manifestations of estrogen stimulation, such as abnormal uterine bleeding. Frequent or persistent abnormal uterine bleeding during treatment is an indication for the study of the endometrium.
If the treatment of irregular menstrual cycles fails, should undertake a survey to exclude organic nature of the disease.
Under the influence of estrogen uterine fibroids may increase in size. In this case, treatment should be discontinued.
It is recommended to discontinue treatment with the development of recurrence of endometriosis on the background .
If you suspect the presence of prolactinoma before treatment to exclude the disease.
In some cases, chloasma may occur, especially in women with a history of chloasma pregnant. During masteron propionate women with a penchant for the emergence of chloasma should avoid exposure to the sun or ultraviolet radiation.
The following conditions may occur, or may be aggravated. Although their relationship with has not been proven, women with these conditions during should be under a doctor’s supervision: epilepsy; breast benign tumor; bronchial asthma; migraine; porphyria; otosclerosis; systemic lupus erythematosus, chorea.
- Medical examinations and counseling
Before starting or resuming masteron propionate woman should undergo a thorough general medical and gynecological examination (including breast examination and cytological examination of cervical mucus), exclude pregnancy. In addition, to exclude blood coagulation disorders. Periodic follow-up examinations should be carried out.
- Effect on results of laboratory tests
Reception of sex steroids may affect biochemical liver function tests, thyroid, adrenals and kidneys, to the content in the plasma transport proteins such as globulin kortikosteroidsvyazyvayuschy and lipid / lipoprotein fractions, carbohydrate metabolism, coagulation and fibrinolysis.
- Effects on ability to drive and use machinery
Does not affect.
In dragees 10 light brown and white 11 pellets were placed in a blister made film and aluminum foil. Each blister with self-adhesive calendar and receive instruction on use is placed in a cardboard box.